Aluminum Toxicity Due to Intravenous Injection of Boiled Methadone

Autor: Gayatri M. Sreenivasan, Raymund L. Yong, Daniel T. Holmes
Rok vydání: 2006
Předmět:
Zdroj: New England Journal of Medicine. 354:1210-1211
ISSN: 1533-4406
0028-4793
DOI: 10.1056/nejmc053341
Popis: To the Editor: A 42-year-old man who was in rehabilitation for intravenous substance abuse presented with a three-month history of seizures and incoordination. Other symptoms included dysarthria, a hesitant pattern of speech, myoclonic jerks, postural tremor, emotional lability, and fluctuating short-term memory. On questioning he admitted that for four years he had been concentrating his methadone preparation, which was diluted with a grape-flavored drink, by heating it in an uncoated aluminum pot. He would then reconstitute the residue for intravenous injection. His serum aluminum level was 6650 nmol per liter (reference interval
Databáze: OpenAIRE