Frusemide in pulmonary oedema: continuous versus intermittent

Autor: F R Zveibil, T Riad, N Makhoul, S Friedstrom
Rok vydání: 1997
Předmět:
Zdroj: Clinical Intensive Care. 8:273-276
ISSN: 1473-7752
0956-3075
DOI: 10.3109/tcic.8.6.273.276
Popis: Objective: To analyse and compare the infusion of frusemide by different modes of administration. Design: Prospective clinical survey of patients suffering from acute respiratory failure due to cardiogenic pulmonary oedema. Setting: A seven-bed general intensive care unit. Patients: Group A comprised 10 patients treated with intravenous frusemide several times daily at a dose of 1 mg/kg. Group B comprised 10 patients treated with continuous infusion of frusemide for 24 hours at an initial dose of 1 mg/kg, and 0.1 mg/kg/hr thereafter, with an option of increasing the dose every 2 hours. Group C comprised 10 patients treated with albumin and frusemide combined in continuous infusion over 24 hours at a dose of 250 mg frusemide diluted in 12.5 g albumin at a rate of 0.1 mg frusemide/kg/hr. Measurements: i) Serum electrolytes, creatinine, blood urea nitrogen (BUN) and protein; ii) urinary electrolytes; iii) hourly urinary output during the first 24 hours after admission. Results: There were no differences in t...
Databáze: OpenAIRE