Pustulosis exantemática aguda generalizada inducida por omeprazol

Autor: Óscar Nantes Castillejo, Ana Valcayo Peñalba, José Manuel Zozaya Urmeneta, José María Martínez-Peñuela Virseda
Rok vydání: 2008
Předmět:
Zdroj: Gastroenterología y Hepatología. 31:295-298
ISSN: 0210-5705
Popis: Acute generalized exanthematous pustulosis (AGEP) comprises a group of eruptions characterized by several small sterile pustules over an erythematous-edematous skin. These eruptions are usually drug induced and show some characteristics that suggest an immunologic background. Treatment is based on withdrawal of the drug causing the eruption. Prognosis is generally good and the skin lesions usually resolve in a few days with characteristic postpustular pin-point desquamation. We report three cases of AGEP induced by omeprazole, a drug with a good safety profile. Some adverse cutaneous reactions have been described as secondary effects. However, to our knowledge, no cases of omeprazole-induced AGEP have previously been reported. AGEP related to other proton pump inhibitors is exceptional.
Databáze: OpenAIRE