Translational In Vivo Models for Women’s Health: The Nonhuman Primate Endometrium—A Predictive Model for Assessing Steroid Receptor Modulators

Autor:	Ov D. Slayden
Rok vydání:	2015
Předmět:	Steroid Receptor Modulators business.industry Menstruation (mammal) Endometriosis Endometrium Bioinformatics medicine.disease Physiological responses Nonhuman primate medicine.anatomical_structure In vivo Immunology Medicine business Hormone
Zdroj:	New Approaches to Drug Discovery ISBN: 9783319289120
DOI:	10.1007/164_2015_22
Popis:	Macaques and baboons display physiological responses to steroid hormones that are similar to those of women. Herein, we describe various uses of nonhuman primates for preclinical studies on menstruation, endometriosis, and as a model system to evaluate reproductive therapies and contraceptives. Our goal is to outline the strengths of the nonhuman primate model for studies leading to improved therapies for women.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b175a27d44e19b1cd85ed801cced771e https://doi.org/10.1007/164_2015_22 Zobrazit plný text záznamu