The effect of a diagonally placed penetrating biodegradable implant on the epiphyseal plate. An experimental study on growing rabbits with special regard to polydioxanone
| Autor: | E. Antero Mäkelä, Pertti Törmälä, Seppo Vainionpää, Pentti Rokkanen, K. Vihtonen, Pertti Helevirta, Matti Mero |
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| Rok vydání: | 1988 |
| Předmět: |
Orthodontics
Varus deformity Materials science business.industry Radiography medicine.medical_treatment Epiphyseal plate Biophysics Anatomy medicine.disease Polydioxanone chemistry.chemical_compound Fixation (surgical) medicine.anatomical_structure chemistry medicine Internal fixation Femur Implant business |
| Zdroj: | Clinical Materials. 3:223-233 |
| ISSN: | 0267-6605 |
| DOI: | 10.1016/0267-6605(88)90059-5 |
| Popis: | Forty rabbits, five weeks of age, were operated on. In 20 rabbits an oblique drill hole of 3.2mm in diameter was made at an angle of 60° to the growth plate of the right distal femur. In the other 20 rabbits a polydioxanone rod was driven in a similar drill hole. The follow-up times were three, six, 12, and 24 weeks. The distal femoral growth plates of both femurs were analyzed by radiographic, microradiographic, oxytetracycline-fluorescence, histological and histomorphometric studies. Histomorphometric studies served as an excellent means of an exact numerical description of the different cellular areas of the growth plate in experimental studies. An oblique drill hole resulted in permanent growth retardation and varus deformity of the femur in growing rabbit. A diagonally placed PDS-implant caused a similar growth retardation but did not cause any varus deformity. Internal fixation of physeal fractures with biodegradable pins with no need of implant removal appears as an exciting prospect. The fixation device should possess suitable mechanical properties to provide a safe aid for fixation and still be sufficiently flexible to permit uneventful healing process. The pressure of growth was able to break the PDS implant. Further studies are needed for development of biodegradable fixation of physeal fractures. |
| Databáze: | OpenAIRE |
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