Synthesis of Ψ[CH(CN)NH] pseudopeptides. A new peptide bond surrogate

Autor:	Rosario Herranz, S. Vinuesa, Ana Martínez, M. Teresa García-López, M.Luisa Suárez-Gea
Rok vydání:	1991
Předmět:	chemistry.chemical_classification Stereochemistry Organic Chemistry Strecker amino acid synthesis Enantioselective synthesis Peptide Biochemistry Catalysis Amino acid Acid catalysis chemistry Drug Discovery Peptide bond Lewis acids and bases
Zdroj:	Tetrahedron Letters. 32:7579-7582
ISSN:	0040-4039
DOI:	10.1016/0040-4039(91)80539-i
Popis:	An easy and versatile general method for the preparation of the new peptide bond surrogate Ψ[CH(CN)NH], by the Lewis acid catalyzed reaction of N-protected α-amino aldehydes with a C-protected amino acid or peptide in the presence of TMSCN, is described.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b136b8354dc7e299dc21f8de651ad3a9 https://doi.org/10.1016/0040-4039(91)80539-i Zobrazit plný text záznamu