Dynamic Radionuclide Labels at Sites of Bone Formation in the Skeleton
| Autor: | E. Polig |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
Radionuclide
Radiation Radiobiology Radiological and Ultrasound Technology Chemistry business.industry Radiochemistry Public Health Environmental and Occupational Health General Medicine Skeleton (computer programming) Labelling Radioactive contamination Dosimetry Radiology Nuclear Medicine and imaging Bone formation Nuclear medicine business |
| Zdroj: | Radiation Protection Dosimetry. 59:213-222 |
| ISSN: | 1742-3406 0144-8420 |
| DOI: | 10.1093/oxfordjournals.rpd.a082653 |
| Popis: | The mean dose and number of hits to nuclei of osteoblasts and their progenitors from expanding volume sources of α-emitters labelling newly formed bone is calculated. It is assumed that these cells only accumulate a radiation dose or nuclear hits during a formation phase. For α-emitters below 6 MeV the dose or number of hits per unit concentration is nearly identical for constant or decreasing mineralisation rate. By means of a simple biokinetic model the amount of recirculating activity and the concentration in sites of bone formation is estimated and results compared with a human injection case. Annual limiting intake levels recommended by ICRP for some transuranics appear to he safe with regard to radiation doses and hit probabilities in formation sites |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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