Finasteride and Its Potential for the Treatment of Female Pattern Hair Loss: Evidence to Date
| Autor: | Poonkiat Suchonwanit, Wimolsiri Iamsumang, Kanchana Leerunyakul |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Pharmacology medicine.medical_specialty business.industry Pharmaceutical Science medicine.disease Dutasteride Dermatology Alternative treatment 03 medical and health sciences chemistry.chemical_compound 030104 developmental biology 0302 clinical medicine Hair loss chemistry 030220 oncology & carcinogenesis Drug Discovery Finasteride medicine Clinical efficacy Adverse effect business Topical minoxidil |
| Zdroj: | Drug Design, Development and Therapy. 14:951-959 |
| ISSN: | 1177-8881 |
| DOI: | 10.2147/dddt.s240615 |
| Popis: | The currently approved treatment for female pattern hair loss (FPHL) includes topical minoxidil administration; however, this treatment fails to achieve hair regrowth in some patients. Finasteride, a selective 5α-reductase inhibitor (5-ARI), may be considered as an alternative treatment. However, because of its potential teratogenic effects, clinical studies and use of finasteride for FPHL are limited. In this review, we aim to summarize the literature regarding the pharmacology, clinical efficacy, and adverse effects of oral finasteride for the treatment of FPHL and to provide novel therapeutic options including topical finasteride and dutasteride, a new generation 5-ARI, for the treatment of FPHL. |
| Databáze: | OpenAIRE |
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