MIS-C and co-infection with P. vivax and P. falciparum in a child: a clinical conundrum. A case report

Autor: Michela Scalisi, Salvatore Giordano, Laura Antonella Canduscio, Maria Concetta Failla, Luca Messina, Elisa Sferrazza, Raffaella Rubino, Lucia Siracusa, Veronica Vanella, Antonio Cascio, Claudia Colomba
Rok vydání: 2022
DOI: 10.21203/rs.3.rs-1486413/v1
Popis: Background: the ongoing Coronavirus Disease 2019 (COVID-19) epidemic represents an unprecedented global health challenge. Many COVID-19 symptoms are similar to symptoms that can occur in other infections. Malaria should always be considered in patients with SARS-CoV-2 infection returning from endemic areas.Case presentation: we present the first case of multisystem inflammatory syndrome (MIS-C) and Plasmodium vivax-falciparum and SARS-CoV2 coinfection in children. Despite clearance of parassitaemia and a negative COVID-19 nasopharyngeal PCR, the patient’s clinical conditions worsened. The World Health Organization (WHO) criteria were used to make the diagnosis of MIS-C. Treatment with intravenous immunoglobulins and methylprednisolone was effective.Conclusions: this case emphasizes the importance of considering malaria diagnosis in patients returning from endemic areas, even in the COVID 19 era. Malaria and SARS-CoV2 co-infection may increase the risk of MIS-C, for which early detection is critical for proper management.
Databáze: OpenAIRE