Process Development and Large-Scale Synthesis of a PDE4 Inhibitor

Autor:	Dwight Macdonald, Antoinette Drahus-Paone, Roy Helmy, Denis Deschenes, Guo-Jie Ho, John Scheigetz, James M. McNamara, Brenda Pipik, Yao-Jun Shi, David A. Conlon, Michel Gallant, Bruno Roy, J. Michael Williams, Anthony Mastracchio
Rok vydání:	2005
Předmět:	chemistry.chemical_compound Scale (ratio) Chemistry Process development Organic Chemistry Quinoline Organic chemistry Physical and Theoretical Chemistry
Zdroj:	Organic Process Research & Development. 10:36-45
ISSN:	1520-586X 1083-6160
Popis:	An efficient, scalable synthesis of the PDE4 inhibitor, 6-[1-methyl-1-(methylsulfonyl)ethyl]-8-(3-{(E)-2-(3-methyl-1,2,4-oxadiazol-5-yl)-2-[4-(methylsulfonyl)phenyl]vinyl}phenyl)quinoline benzenesu...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b0e5ea4b5cc94d87e173aec7aa586840 https://doi.org/10.1021/op050116l Zobrazit plný text záznamu