ChemInform Abstract: Copper(II)-Catalyzed Oxidation of 4-Carboxythiazolines and 4-Carboxyoxazolines to 4-Carboxythiazoles and 4-Carboxyoxazoles

Autor:	Jinyi Xu, Hequan Yao, Changhua Tang, Yiyun Wang, Xiaoming Wu, Ziyuan Li, Yue Huang
Rok vydání:	2012
Předmět:	chemistry.chemical_classification chemistry.chemical_compound Hydrolysis chemistry Group (periodic table) Aryl chemistry.chemical_element General Medicine Ring (chemistry) Medicinal chemistry Copper Alkyl Catalysis
Zdroj:	ChemInform. 43
ISSN:	0931-7597
Popis:	A mild copper(II)-catalyzed oxidation of 4-carboxythiazolines and 4-carboxyoxazolines to 4-carboxythiazoles and 4-carboxyoxazoles has been developed. Various substrates with alkyl or aryl substitutions at 2-position on azoline ring could be smoothly oxidized to the desired products in good to excellent yields. Moreover, the hydrolysis of the ester group could be avoided under this method.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b0de6e18e873cb6af64b7fdefe9814d6 https://doi.org/10.1002/chin.201205034 Zobrazit plný text záznamu Plný text