| Autor: | Scott L. Lauren, Olaf B Kinstler, Amiee G. Paige, James B. Hamburger, Michael J. Treuheit, David N. Brems |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Pharmacology
Methionine Chromatography Stereochemistry fungi Organic Chemistry technology industry and agriculture Pharmaceutical Science Polyethylene glycol law.invention chemistry.chemical_compound Residue (chemistry) chemistry Covalent bond law PEG ratio Recombinant DNA Molecular Medicine Molar mass distribution Pharmacology (medical) Derivatization Biotechnology |
| Zdroj: | Pharmaceutical Research. 13:996-1002 |
| ISSN: | 0724-8741 |
| DOI: | 10.1023/a:1016042220817 |
| Popis: | Purpose. The liquid stability of rhG-CSF was investigated after polyethylene glycol (PEG) with an average molecular weight of 6000 daltons was covalently attached to the N-terminal methionine residue. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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