Nitriles: an attractive approach to the development of covalent inhibitors

Autor:	Vinícius Bonatto, Rafael F. Lameiro, Fernanda R. Rocho, Jerônimo Lameira, Andrei Leitão, Carlos A. Montanari
Rok vydání:	2023
Předmět:	Pharmacology Organic Chemistry Drug Discovery Pharmaceutical Science Molecular Medicine Biochemistry
Zdroj:	RSC Medicinal Chemistry. 14:201-217
ISSN:	2632-8682
Popis:	This review highlights the roles of nitriles in covalent inhibitors, their reactivity, examples of pharmaceuticals containing the cyano group and recent developments of nitrile-based inhibitors.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b0c465b20a6fe88dc303afa7504aec8f https://doi.org/10.1039/d2md00204c Zobrazit plný text záznamu