NQPC-1 INSIGHTS FROM PREOPERATIVE FATIGUE ASSESSMENT IN GLIOMA PATIENTS

Autor: Takuro Sakurai, Toshihisa Nakashima, Mayumi Horikawa, Yoichi Shimizu, Naoko Inamura, Ai Sumiyoshi, Aiko Matsuoka, Mami Oki, Noriko Watanabe, Yusuke Okita, Shota Yokota, Risa Abe, Kaneyuki Ichikawa, Yasuji Miyakita, Masamichi Takahashi, Makoto Ohno, Shunsuke Yanagisawa, Akira Kawai, Yoshitaka Narita
Rok vydání: 2022
Předmět:
Zdroj: Neuro-Oncology Advances. 4:iii18-iii18
ISSN: 2632-2498
DOI: 10.1093/noajnl/vdac167.069
Popis: Introduction Glioma is a rare type of tumor, and the research on fatigue and QOL in glioma patients is limited. Research from other countries has reported patients with intense fatigue in the preoperative stage, but no similar studies could be found in Japan. In the present study, we report a retrospective investigation of fatigue assessment performed during preoperative rehabilitation evaluation. Participants and Methods Participants were 90 patients admitted to the hospital for glioma surgery between January 2016 and December 2020 who underwent five specific preoperative evaluations: KPS, MMSE, Motor-Functional Independence Measure (Motor FIM), Cancer Fatigue Scale (CFS), and grip strength. Participants were divided into a CFS-High(CFS-H) group (CFS>19 points) and a CFS-Low (CFS-L) group (CFS Results Participants were 90 patients with high-grade glioma. Fifty-seven were men, and the median age was 45 (15-81). Thirty-three participants (37%) had intense fatigue before surgery (CFS-H group: 33 participants, CFS-L group: 57 participants). In the CFS-H group and CFS-L group respectively, age was 46.5/44 (p=0.36), MMSE was 24 points/29 points (p=0.00255), Motor FIM was 89 points/91 points (p=0.0383), and grip strength was 22.2kg/25.5kg (p=0.194). Discussion The present study suggests that some Japanese high-grade glioma patients also experience intense fatigue before surgery. Compared to patients with low fatigue, those with high fatigue were suggested to have significant declines in cognitive function and ADL.
Databáze: OpenAIRE