Embryonal Rhabdomyosarcoma of the Uterine Cervix: Two Cases Report and Literature Review

Autor:	Hachani Faten, Boukadida Asma, Mouna Kouira, Khairi Hedi, Essaidi Habib, Hidar Samir, Meddeb Sawssen, Khlifi Abdeljalil, Bibi Mohamed
Rok vydání:	2014
Předmět:	medicine.medical_specialty Chemotherapy business.industry medicine.medical_treatment medicine.disease Surgery Radiation therapy Uterine cervix Medicine In patient Vaginal bleeding Embryonal rhabdomyosarcoma Radical surgery medicine.symptom business Rhabdomyosarcoma
Zdroj:	Open Journal of Obstetrics and Gynecology. :868-873
ISSN:	2160-8806 2160-8792
DOI:	10.4236/ojog.2014.414122
Popis:	Introduction: Embryonal rhabdomyosarcoma (RMS) of the uterine cervix is a rare and extremely aggressive malignant entity. However, prognosis seems to be improved with the use of multimodality approach treatment. Cases: We report the cases of 50- and 51-year-old women, presenting with vaginal bleeding and mass. The two patients underwent radical surgery. Histological examination revealed RMS of uterine cervix. Treatment was effective in the first case but despite the chemotherapy, the second patient died two months later. Discussion and Conclusions: The prognosis of the cervical embryonal RMS depends on clinical and histological features. The current treatment protocols are based on trials done on pediatric patients. Studies on embryonal RMS treatment and outcomes are limited in women over forty years. In patients with unfavorable prognosis characteristics, the multimodality approach including surgery, adjuvant chemo and radiotherapy can be effective. Otherwise, surgery alone can effectively be proposed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b0a4bc60cb7d2d27ef5fcebfe1221636 https://doi.org/10.4236/ojog.2014.414122 Zobrazit plný text záznamu