Caesarean Section has no impact on lung function at the age of 15 years
| Autor: | Holger Schulz, Zhengcun Pei, Elisabeth Thiering, Joachim Heinrich, Sibylle Koletzko, Andrea von Berg, Barbara Hoffmann, Dietrich Berdel, Claudia Flexeder, Carl-Peter Bauer, Irene Brüske |
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| Rok vydání: | 2015 |
| Předmět: |
Pulmonary and Respiratory Medicine
Pediatrics medicine.medical_specialty education.field_of_study Childhood asthma Vaginal delivery business.industry medicine.medical_treatment Population medicine.disease respiratory tract diseases Pediatrics Perinatology and Child Health Epidemiology medicine Caesarean section education business Lung function Asthma Full Term |
| Zdroj: | Pediatric Pulmonology. 50:1262-1269 |
| ISSN: | 8755-6863 |
| Popis: | Epidemiological studies and meta-analyses have shown an increased risk of childhood asthma for children born by Caesarean Section (C-Section).To investigate the effect of delivery by C-Section on lung function and asthma in adolescence in a population-based prospective birth cohort of healthy full term newborns.Questionnaire data on mode of delivery and asthma as well as spirometric measurements were available for 1850 adolescents at the age of 15 years, who participated in a follow-up examination of the GINIplus study. Linear regression models were used to examine associations between mode of delivery and lung function parameters. Two reference populations (Lunokid and GLI) were used to calculate the standardized z-scores of lung function parameters.The mean difference in lung function parameters for adolescents born by C-Section, compared to vaginal delivery was not statistically significant. The risk for developing asthma by the age of 15 years was not higher in children born by C-Section-OR: 0.87 (95% CI: 0.57, 1.33) adjusted for sex, age, study center, and parental education level.C-Section was not associated with impaired lung function or an increased risk of asthma at the age of 15 years in our birth cohort of healthy full term neonates. |
| Databáze: | OpenAIRE |
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