Diffuse optical imaging of the newborn infant brain

Autor:	Jeremy C. Hebden, Nick Everdell, Topun Austin, Marta Varela, Adam Gibson, Judith Meek, Salavat Magazov
Rok vydání:	2012
Předmět:	Pathology medicine.medical_specialty medicine.diagnostic_test business.industry Hemodynamics Oxygenation medicine.disease Infant newborn Diffuse optical imaging Intraventricular hemorrhage medicine.anatomical_structure Cerebral cortex Medical imaging medicine Optical tomography business
Zdroj:	ISBI
DOI:	10.1109/isbi.2012.6235595
Popis:	Diffuse optical imaging has been developed at University College London (UCL) as a new method of assessing cerebral function and pathology in the newborn infant brain. The technique exploits the relative transparency of biological tissue to near-infrared light (700–1000nm) and the wavelength dependent absorption characteristics of hemoglobin, which vary with oxygenation. Methods have been developed to localize rapid hemodynamic changes resulting from functional activation of the cerebral cortex, and to generate three-dimensional images representing the spatial variation in cerebral blood volume and oxygenation. Previous studies have also been made of the brains of infants with intraventricular hemorrhage, hypoxic-ischemic injury, and epileptic seizures. This paper summarizes preliminary measurements performed with a new time-resolved system.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b090217baa4683d8dd0e98e6dc7ebc83 https://doi.org/10.1109/isbi.2012.6235595 Zobrazit plný text záznamu