Effects of age and ischemia on levels of lipoperoxides and lipid-soluble antioxidants in the human heart
| Autor: | Makarova Mn, Afanas'ev Sa, Alekseeva Ed, A. M. Chernyavskii, Lebedev Av, Sh. D. Akhmedov, Karpov Rs, M. V. Pekarskaya |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
medicine.medical_specialty
Radical Ontogeny Vitamin E medicine.medical_treatment Cardiac muscle Ischemia Human heart General Medicine Absorption (skin) medicine.disease General Biochemistry Genetics and Molecular Biology Lipid peroxidation chemistry.chemical_compound medicine.anatomical_structure Endocrinology Biochemistry chemistry Internal medicine medicine |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 119:561-563 |
| ISSN: | 1573-8221 0007-4888 |
| DOI: | 10.1007/bf02443689 |
| Popis: | Levels of lipoperoxides and hydrophobic scavengers of free radicals were estimated in n-hexane extracts of myocardial biopsy specimens taken from cardiac patients (children and adults) during surgical operations. Ultraviolet spectra of these extracts were found to contain four absorption bands with peaks at 214, 233, 258, and 298 nm that characterize the levels of diene and triene conjugates. A comparison of the data obtained for children and adults suggested that the total antiradical activity of the cardiac muscle decreases while its content of vitamin E remains virtually unchanged during ontogeny. Significantly reduced vitamin E levels were noted in specimens from patients with chronic ischemic heart disease. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink