Water vs. desiccant. Improvement of Yb-BINOL complex catalyzed enantioselective epoxidation of enones

Autor:	Masakatsu Shibasaki, Yukari Kobayashi, Takayoshi Arai, Hiroaki Sasai, Masahiro Bougauchi, Shizue Watanabe
Rok vydání:	1998
Předmět:	Desiccant Chemistry Organic Chemistry Drug Discovery Enantioselective synthesis Organic chemistry Molecular sieve Biochemistry Catalysis
Zdroj:	Tetrahedron Letters. 39:7353-7356
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(98)01578-0
Popis:	The Yb-BINOL-complex-catalyzed enantioselective epoxidation of α,β-unsaturated ketones (enones) was greatly improved by addition of a small amount of water (ca. 5 equiv to Yb). Optimized conditions and a plausible mechanism of the role of water and molecular sieves in asymmetric epoxidation are also described.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b06d0b76fee3da902e706d357a60f427 https://doi.org/10.1016/s0040-4039(98)01578-0 Zobrazit plný text záznamu Full Text from ScienceDirect