Serum sialic acid in acute oral bacterial infections

Autor:	Masao Nagumo, Akiyuki Nishimura, Kimitoshi Yagami, Yoko Iwai, Masami Kou, Shinya Ito, Masayasu Iwase
Rok vydání:	1986
Předmět:	chemistry.chemical_classification business.industry Acute-phase protein Serum concentration Sialic acid Microbiology carbohydrates (lipids) chemistry.chemical_compound Enzyme chemistry Immunology Medicine In patient Glycoprotein business
Zdroj:	Japanese Journal of Oral & Maxillofacial Surgery. 32:380-385
ISSN:	2186-1579 0021-5163
DOI:	10.5794/jjoms.32.380
Popis:	Serum sialic acid in patients with acute oral bacterial infections and healthy parsons was measured by enzymatic method. Significant raised levels of serum sialic acid were found in patients with acute infections as compared with healthy persons. Serum levels of sialic acid corresponded with the clinical condition of infections diseases and recovered normally with clinical improvement. Serum concentrations of sialic acid were well correlated with those of C-reactive protein and numbers of white blood cells. In addition, serum sialic acid significantly increased postoperatively.As human serum does not contain free sialic acid and sialic acid almost binds to glycoprotein such as C-reactive protein, acid glycoprotein, and so on, these results suggest that raised levels of serum sialic acid may be caused by the increase of acute phase proteins. Therefore, measurement of serum sialic acid is thought to be useful as a marker which reflects the clinical condition of infections diseases rather than infections themselves.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b06949f7fd804c9aad268e7f815139cc https://doi.org/10.5794/jjoms.32.380 Zobrazit plný text záznamu