Periorbital necrobiotic xanthogranuloma and stage I multiple myeloma
| Autor: | Harold Plotnick, Yoshiki Taniguchi, Liborio Tranchida, William G. Negendank, Ken Hashimoto |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Pathology
medicine.medical_specialty integumentary system medicine.diagnostic_test business.industry government.form_of_government Magnetic resonance imaging Dermatology medicine.disease eye diseases Lymphatic Endothelium medicine.anatomical_structure medicine government Ultrastructure Bone marrow Eyelid business Necrobiotic xanthogranuloma Histiocyte Dexamethasone medicine.drug |
| Zdroj: | Journal of the American Academy of Dermatology. 25:373-377 |
| ISSN: | 0190-9622 |
| DOI: | 10.1016/0190-9622(91)70208-j |
| Popis: | We observed a 40-year-old woman with necrobiotic xanthogranuloma from the inception of indurated eyelid and periorbital infiltrates and concurrent stage I multiple myeloma to resolution of infiltrates in skin and bone marrow after pulsed high-dose oral dexamethasone therapy. Ultrastructural studies revealed lipid vacuoles in epidermal keratinocytes, in dermal histiocytic macrophages, and in vascular and lymphatic endothelial cells. The presence of lipid vacuoles in epidermal keratinocytes has not been reported previously in xanthogranuloma. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|