Modelling the gas chromatographic separation of multicomponent samples on a system of three open-tubular columns coupled in series

Autor: Jacques R. Chrétien, T. Hevesi, Ján Krupčík
Rok vydání: 1995
Předmět:
Zdroj: Fresenius' Journal of Analytical Chemistry. 352:643-648
ISSN: 1618-2650
0937-0633
DOI: 10.1007/bf00323040
Popis: A procedure was developed for modelling the gas chromatographic separation on a system of columns coupled in series. This procedure can be used for computer based optimization of lengths and order of serially coupled columns at isothermal conditions. The sample component retention factors and column resistances needed for the model can easily be measured on each individual column. The proposed procedure was verified by analyzing a 52 component hydrocarbon mixture on three columns of different polarity coupled in series by various column orders. Good agreement between experimental and calculated retention data was found. The procedure is also well suited for optimization of the chromatographic selectivity by coupling columns with different selectivity in series.
Databáze: OpenAIRE
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