Evaluation of mast cells in periapical cysts, dentigerous cysts, and keratocystic odontogenic tumors
| Autor: | Eliene Carvalho da Fonseca, Licínio Esmeraldo da Silva, Simone De Queiroz Chaves Lourenço, Fábio Ramôa Pires, Juliana de Noronha Santos Netto |
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| Rok vydání: | 2012 |
| Předmět: |
Cancer Research
Pathology medicine.medical_specialty Periapical cyst biology business.industry Tolonium chloride Connective tissue Odontogenic tumor medicine.disease Mast cell Pathology and Forensic Medicine Dentigerous cyst chemistry.chemical_compound medicine.anatomical_structure Otorhinolaryngology chemistry medicine biology.protein Periodontics Immunohistochemistry Oral Surgery Antibody business |
| Zdroj: | Journal of Oral Pathology & Medicine. 41:630-636 |
| ISSN: | 0904-2512 |
| Popis: | J Oral Pathol Med (2012) 41: 630–636 Background: Several cell types are associated with the development of cystic and tumoral odontogenic lesions. Among inflammatory cells, mast cells can be associated with their pathogenesis. The aim of this study was to analyze mast cells in periapical cysts, dentigerous cysts, and keratocystic odontogenic tumors. Methods: Tissue sections were submitted to toluidine blue staining and immunohistochemistry with antibody anti-tryptase (clone G3). Mast cells were quantitated using Image-Pro Plus software to obtain the mean number of mast cells in three regions: epithelial, superficial portion of the fibrous wall and deep portion of the fibrous wall from 20 periapical cysts, 20 dentigerous cysts (six non-inflamed and 14 inflamed) and 20 keratocystic odontogenic tumors (four non-inflamed and 16 inflamed). Results: The mean number of mast cells detected per lesion by immunohistochemistry (4.1) was higher than by histochemistry (1.5) (P |
| Databáze: | OpenAIRE |
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