Incidence and Prognostic Significance of Immunophenotypic Subgroups in Childhood Acute Lymphoblastic Leukemia: The Experience of the AIEOP Cooperative Study

Autor: A Cantù Rajnoldi, Cesare Guglielmi, M Saitta, A Lippi, Donatella Granchi, Maurizio Aricò, Giuseppe Basso, Andrea Biondi, T. Santostasi, Nicola Santoro, M. G. Cocito, M. C. Putti, M. G. Russo, Andrea Pession, Roberto Rondelli
Rok vydání: 1993
Předmět:
Zdroj: Recent Advances in Cell Biology of Acute Leukemia ISBN: 9783642848971
DOI: 10.1007/978-3-642-84895-7_26
Popis: The role of immunological phenotype in childhood acute lymphoblastic leukemia’s (ALL) is important in classifying the different origins of ALL, but the identification of different subgroups of clinical relevance is still under discussion. In fact, frequent discrepancies are observed in the prognostic value of immunological subgroups in individual series. A poor outcome was seen in immunophenotype T in the first clinical studies (Greaves et al. 1981), but these results have not always been confirmed and now the T origin of ALL is not considered a prognostic factor (Hammond et al. 1986).
Databáze: OpenAIRE