Comparative Study of Aqueous and Ethanolic Leaf Extracts Of Spondias Mombin on Neurobehaviour in Male Rats

Autor:	AO Igiri, O. R. Asuquo, OE Mesembe
Rok vydání:	2013
Předmět:	Aqueous extract Elevated plus maze Traditional medicine biology business.industry medicine.drug_class biology.organism_classification Body weight Anxiolytic Anesthesia Male rats Sedative agent Medicine Stretch attempt business Spondias mombin
Zdroj:	IOSR Journal of Pharmacy and Biological Sciences. 5:29-35
ISSN:	2278-3008 2319-7676
DOI:	10.9790/3008-0522935
Popis:	Remedies for anxiety and fear have been investigated through both orthodox and traditional medicine; this study compared the effects of chronic administration of graded doses of aqueous and ethanolic extracts of Spondias mombin on anxiety and fear in Albino Wistar rats. Fifty rats of Wistar strain (100-120g body weight) were divided into five major groups A-E with each group made up of ten rats (n=10). Spondias mombin (250, 400,500 and 800mg/kg) were orally administered for 4 weeks before testing. The elevated plus maze was used to assess anxiety behaviour. Following administration of graded doses of aqueous and ethanolic extracts of Spondias mombin for a period of four weeks, decreased anxiety and fear in the albino rats was revealed (p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b02e6fb89b98595f9b5125351e0e25b2 https://doi.org/10.9790/3008-0522935 Zobrazit plný text záznamu