First Total Synthesis of (3R,4S)-4-Hydroxylasiodiplodin: A Facile and Stereoselective Approach

Autor:	Gyan Chander Eppa, Saibal Das, Sheshurao Bujaranipalli
Rok vydání:	2013
Předmět:	chemistry.chemical_compound Natural product chemistry Methyl acetoacetate Organic Chemistry Total synthesis Organic chemistry Organic synthesis Stereoselectivity Metathesis 4-hydroxylasiodiplodin
Zdroj:	Synlett. 24:1117-1120
ISSN:	1437-2096 0936-5214
DOI:	10.1055/s-0032-1317805
Popis:	A first total synthesis of (3R,4S)-4-hydroxylasiodiplodin is described starting from methyl acetoacetate and a commonly available carbohydrate, d -mannitol, which is regularly used in organic synthesis. The facile and stereoselective approach involves the Barbier allylation and a ring-closing metathesis as key steps.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b02663bb5e61d341510a9afa3eedb78c https://doi.org/10.1055/s-0032-1317805 Zobrazit plný text záznamu