Matching degree between PI3K/AKT/mTOR (PAM) pathway mutations (mut) and therapy (ttx) as predictor of clinical benefit (ClinBen) in early trials

Autor:	Ana Maria Martinez de Castro, Paolo Nuciforo, Irene Brana, Ana Vivancos, Cinta Hierro, Cristina Saura, Ana Oaknin, Jordi Rodon Ahnert, Maria Ochoa de Olza, Rodrigo Dienstmann, Juan Martin Liberal, Analia Azaro, Cristina Cruz Zambrano, Josep Tabernero, Mafalda Oliveira, Helena Aguilar, Guillem Argiles, Elena Sanchez
Rok vydání:	2016
Předmět:	Oncology congenital hereditary and neonatal diseases and abnormalities Cancer Research medicine.medical_specialty Matching (statistics) Degree (graph theory) business.industry Internal medicine medicine business Protein kinase B PI3K/AKT/mTOR pathway
Zdroj:	Journal of Clinical Oncology. 34:2572-2572
ISSN:	1527-7755 0732-183X
Popis:	2572Background: Drugs targeting aberrations in the PAM pathway are in clinical development but it is not completely clear if mut and ttx matching increases chances of ClinBen. Methods: Retrospectiv...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::affdc2609fda8e74d666ecdc0611feb9 https://doi.org/10.1200/jco.2016.34.15_suppl.2572 Zobrazit plný text záznamu