Synthesis of novel pyrido[3′,2′:5,6]thiopyrano[3,2‐ b ]indol‐5(6 H )‐ones and 6 H ‐pyrido[3′,2′:5,6]thiopyrano[4,3‐ b ]quinolines, two new heterocyclic ring systems

Autor: Francesca Simorini, Gianluca Pardi, D. Bertini, Giampaolo Primofiore, Anna Maria Marini, Concettina La Motta, Federico Da Settimo, Silvia Salerno, Antonio Da Settimo
Rok vydání: 2002
Předmět:
Zdroj: Journal of Heterocyclic Chemistry. 39:1001-1006
ISSN: 1943-5193
0022-152X
DOI: 10.1002/jhet.5570390522
Popis: The synthesis of new pyrido[3′,2′:5,6]thiopyrano[3,2-b]indol-5(6H)-ones was accomplished by the Fischer-indole cyclization of some 2,3-dihydro-3-phenylhydrazonothiopyrano[2,3-b]pyridin-4(4H)-ones, obtained from the 2,3-dihydro-3-hydroxymethylenethiopyrano[2,3-b]pyridin-4(4H)-one, by the Japp-Klingemann reaction. 6H-Pyrido[3′,2′:5,6]thiopyrano[4,3-b]quinolines were obtained by reaction of 2,3-dihydrothiopyrano-[2,3-b]pyridin-4(4H)-ones with o-aminobenzaldehyde or 5-substituted isatins. The preparation of some derivatives, functionalized with an alkylamino-substituted side chain, is also described.
Databáze: OpenAIRE
Externí odkaz: