| Popis: |
Confusion remains a frequent event appearing during cancer course; many causes have to be excluded, including antitumoral agent-induced encephalopathy. Ifosfamide-induced encephalopathy is often underdiagnosed due to aspecific symptoms. The manifestations of this encephalopathy are usually moderate and spontaneously reversible but may also lead to coma and death. We describe symptoms of dysarthria and ataxia appearing following the second course of ifosfamide in a patient treated for sarcoma. Furthermore, methylene blue administration instantaneously reversed the process. This case report highlights an atypical presentation of encephalopathy induced by ifosfamide and the importance to consider methylene blue in this setting. |
