Meningoencephalitis case with listeriosis etiology in an immunocompetent female patient
| Autor: | Vitaliy A. Gridasov, Olga N. Domashenko |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Meningitides
Anisocoria medicine.medical_specialty business.industry 030231 tropical medicine Meningoencephalitis medicine.disease_cause medicine.disease Meropenem Gastroenterology Penicillin 03 medical and health sciences 0302 clinical medicine Listeria monocytogenes Internal medicine medicine Etiology 030212 general & internal medicine Leukocytosis medicine.symptom business medicine.drug |
| Zdroj: | Epidemiology and Infectious Diseases. 25:41-44 |
| ISSN: | 2411-3026 1560-9529 |
| DOI: | 10.17816/eid35183 |
| Popis: | Nervous forms of listeriosis are observed in 5%10% of persons suffering from this disease and in 75% of children with bacteriologically confirmed listeriosis as well. The most widespread clinical variant is Listeria meningitis, making up 15% of all cases of bacterial and serous meningitides. The mortality rate at neurolisteriosis reaches 30%40%. A case of acute meningoencephalitis associated with Listeria monocytogenes 4b in a 37-year-old immunocompetent woman is described. The disease was characterized by subacute onset, manifested intoxication, long-lasting and high-grade fever, cerebral coma, bulbar syndrome, right-side hemiparesis, bilateral hypertonus of the wrist flexors, strabism, anisocoria, manifested leukocytosis with leukocyte formula stab shift, ESR 4559 mm/hour. Cerebrospinal fluid test: cytosis 663 сells in 1 mcl, neutrophils 79%, lymphocytes 21%, protein 1451 mg/l, glucose 3.8 mmol/l. Diagnosis had been confirmed with detection of IgM against Listeria monocytogenes 4b in liquor using the indirect immunofluorescence reaction and Listeria monocytogenes by means of PCR. Antibacterial therapy had been conducted using Meropenem, Ampicillinum, endolumbal administration of 4 mg once daily of Gentamycinum combined with intravenous administration of 24 million of units/day of Penicillin. On day 50, she was transferred for rehabilitation treatment to the Department of Neurology. |
| Databáze: | OpenAIRE |
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