The occurrence of Pneumocystis jirovecii in people from three different age groups of Warsaw (Poland) community

Autor: Tadeusz H. Dzbeński, Marek T. Szkoda, Elżbieta Gołąb, Małgorzata Sadkowska-Todys
Rok vydání: 2008
Předmět:
Zdroj: Acta Parasitologica. 53
ISSN: 1896-1851
1230-2821
DOI: 10.2478/s11686-008-0003-1
Popis: The three age groups of people from Warsaw: children, young adults and elderly people were examined for the prevalence of infection with Pneumocystis jirovecii. Nested PCR was used to amplify fragment of mitochondrial large subunit rRNA of the fungus in samples of oropharyngeal swabs. Nineteen (12.8%) of the 148 examined samples were positive for DNA of P. jirovecii. The samples collected from children were more often positive than the samples from young adults (p = 0.003) or from both groups of adults (p = 0.0029). Moreover, among adults (n = 99) proportion of infected women (n = 6; 12.5%) was significantly higher than men (n = 1; 2%). Results of the research confirm the high prevalence of Pneumocystis infection in children and indirectly point out to children as a possible source of infection for older people.
Databáze: OpenAIRE
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