Paget's disease of the male breast. A case report with cytokeratin 7-negative variant

Autor: Juan Mosquera-Reboredo, Benigno Acea-Nebril, Alberto Bouzón-Alejandro
Rok vydání: 2022
Předmět:
Zdroj: Revista de Senología y Patología Mamaria. 35:S7-S10
ISSN: 0214-1582
DOI: 10.1016/j.senol.2021.06.001
Popis: Paget's disease (PD) of the male breast represents less than 2% of male breast cancer. The diagnosis usually delays about 8 months, until it is decided to biopsy the nipple–areola complex lesion. Immunohistochemical techniques help us to differentiate it from other diseases that affect the nipple–areola complex. Most of the patients present an underlying breast carcinoma, which conditions the prognosis. Mastectomy with sentinel lymph node biopsy is the initial treatment in clinically node-negative patients. Two systematic reviews have collected 57 cases of PD of the breast in men published up to 2016. We report an unusual case of mammary PD in a male patient with cytokeratin 7-negative variant.
Databáze: OpenAIRE