Comparison of Coronary Artery Calcification in Peritoneal and Hemodialysis Patients

Autor: Hung Jung Wang, Ting-Kai Leung, Pzen Wen Chen, Ching Huei Kung, Ya Yen Chen, Yi Hsiang Lin, Wen Tien Hsiao, Chi Ming Lee
Rok vydání: 2011
Předmět:
Zdroj: Journal of Experimental & Clinical Medicine. 3:89-92
ISSN: 1878-3317
Popis: Background/Purpose Cardiovascular disease accounts for more than 50% of deaths among patients with end-stage renal disease, and numerous factors have been proposed that may contribute to this increased risk of death. Coronary artery calcification has been recognized as one of the important risk factors for cardiovascular disease in patients undergoing dialysis. The aim of this study was to compare the coronary artery calcification score (CACS) in peritoneal dialysis (PD) and hemodialysis (HD) patients, and to assess the effect of dialysis during a 12-month period. Methods Multidetector computed tomography was performed in 33 chronic dialysis patients (15 PD and 18 HD patients; mean age, 54 years) at Months 1, 6, and 12 during the study period. Blood samples were collected from each patient monthly to measure the serum levels of calcium and phosphorus. Results The CACSs were significantly increased at Month 12 versus Month 1 in both PD and HD patients (p Conclusions Our data suggest that the increase in CACS is not different between the PD and HD patients. Furthermore, the decrease in CACS between Months 7 and 12 suggests that there could be a factor other than the level of the calcium–phosphorus product that accounts for the variation in CACS in both groups.
Databáze: OpenAIRE