Probing organic-mineral interface in intact bone using magic angle spinning solid state NMR

Autor:	Danielle Laurencin, Ondřej Nikel, Deepak Vashishth, S. Besdos
Rok vydání:	2011
Předmět:	Materials science Mineral Interface (Java) Analytical chemistry chemistry.chemical_element Pulse sequence medicine.anatomical_structure Solid-state nuclear magnetic resonance Chemical engineering chemistry Phase (matter) medicine Magic angle spinning Cortical bone Carbon
Zdroj:	2011 IEEE 37th Annual Northeast Bioengineering Conference (NEBEC).
Popis:	Organic-mineral interface plays an important role in defining the mechanical properties of bone. Ability to probe this poorly understood interface at the molecular level in intact bone is desirable, and solid state NMR is one of the few techniques available for this. An intact cortical bone was successfully machined and spun at 12.5kHz. The 13C-31P REDOR pulse sequence was used on a powdered bovine bone to mark carbon environments that are spatially proximate to the surface of mineral phase, thereby giving direct insight on the structure of the organic-mineral interface.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::af7edf4f5ed2630ce88444f905de3caa https://doi.org/10.1109/nebc.2011.5778686 Zobrazit plný text záznamu