Interpretable Diagnosis of ADHD Based on Wavelet Features and Logistic Regression
| Autor: | Julián D. Pastrana-Cortes, Paula Marcela Herrera-Gómez, Maria Camila Maya-Piedrahita, David Cárdenas-Peña, Álvaro-Ángel Orozco-Gutierrez |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.diagnostic_test
Computer science business.industry Electroencephalography Machine learning computer.software_genre medicine.disease Logistic regression Wavelet Social skills medicine Attention deficit hyperactivity disorder Artificial intelligence Medical diagnosis F1 score business computer Interpretability |
| Zdroj: | Progress in Artificial Intelligence and Pattern Recognition ISBN: 9783030896904 IWAIPR |
| DOI: | 10.1007/978-3-030-89691-1_41 |
| Popis: | Despite arising in childhood, attention deficit hyperactivity disorder (ADHD) can persist into adulthood, compromising the individual’s social skills. ADHD diagnosis is a real challenge due to its dependence on the clinical observation of the patient, the information provided by parents and teachers, and the clinicians’ expertise. Therefore, there is great interest in studying objective biomarkers extracted from electroencephalographic (EEG) signals supporting accurate diagnoses. However, the non-stationarity and non-linearity characteristics of the EEG hinders the development of such tools. This paper presents a methodology for supporting the ADHD diagnosis by extracting features from the Discrete Wavelet transform of EEG signals. Due to the failed inhibitory control symptom, we consider EEG signals recorded under the Reward Stop Signal Task paradigm. Then, the logistic regressor learns the linear boundary discriminating between ADHD and healthy control subjects. As a benefit, the weighting vector supporting the classification also provides a straightforward interpretation of features in spatial locations and decomposition levels. The cross-validated classification results prove that the approach reaches an F1 score of \(96\%\) on a dataset of 34 children. Besides, the interpretability results support the hypothesis that the motivational effect leads the poor impulse control in ADHD. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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