Overview on Sclerodermal Renal Crisis

Autor: Marawn Fahad H. Altemani, Waleed Farhan D. Alshammari, Nuwayr Hamdan D. Albalawi, Reema Abdulrahman A. Alanazi, Shahad Saad A. Aljoaid, Abeer Abdulrhman. Basmih, Abrar Ali M. Aldhameen, Jalawi Talal A. Alotaibi, Mona Khalid M. Alqubali, Mahdi Ali M. Alyami, Tariq Bander F. Alanazi, Muflih Abdullah S. Albalawi
Rok vydání: 2021
Předmět:
Zdroj: Journal of Pharmaceutical Research International. :88-95
ISSN: 2456-9119
DOI: 10.9734/jpri/2021/v33i36b31954
Popis: Usually, malignant high blood pressure and severe renal damage are main characters in SSc. SRCs is a relatively rare condition, found in approximately 5% of all SSc patients. This study was carried out to summarize the contemporary evidence regarding the causes, risk factors, manifestations, management and prognosis of Sclerodermal Renal Crisis‎.‎ a simple review was carried out, searching databases PubMed, Google Scholar, and EBSCO. The authors extracted the needed data and stated that SRCs continues to be a rare diagnosis affecting up to six percent of SSc patients, but has a high morbidity and death influence. SRCs presentation is varied, with hypertension, normal BP and renal insufficiency. Medics should be minded by potential SRCs presentations. Early detection and initiation of aggressive ACEi antihypertensive medication in ED could enhance patient outcomes and around 60% of SRCs patients need dialysis.
Databáze: OpenAIRE