Remote stereocontrol by sulfinyl groups: asymmetric alkylation of chiral 2-p-tolylsulfinyl benzyl carbanions

Autor:	Margarita Puente, José L. García Ruano, M. Teresa Aranda
Rok vydání:	2005
Předmět:	chemistry.chemical_compound Chemistry Stereochemistry Organic Chemistry Drug Discovery Sulfoxide Alkylbenzenes Alkylation Biochemistry Carbanion Sequence (medicine)
Zdroj:	Tetrahedron. 61:10099-10104
ISSN:	0040-4020
DOI:	10.1016/j.tet.2005.08.014
Popis:	Alkylation reactions of the benzyllithiums derived from enantiomerically pure 2-p-tolylsulfinyl alkylbenzenes have been carried out with excellent yields and high de. A lithiation-substitution sequence, stereochemically controlled by a remote sulfoxide, accounts for the experimental results.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::af2cce5837186a449e50972b30fa9b7e https://doi.org/10.1016/j.tet.2005.08.014 Zobrazit plný text záznamu Full Text from ScienceDirect