Synthesis and Structural and Initial Cancer Cell Line Characterization of Organotin Polyesters from Dipicolinic Acid
| Autor: | Alisa Moric-Johnson, Charles E. Carraher, Floyd Russell, Michael R. Roner, Lindsey Miller, Paul Slawek, Jeffrey D. Einkauf |
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| Rok vydání: | 2016 |
| Předmět: |
chemistry.chemical_classification
Materials science Polymers and Plastics Inorganic chemistry Infrared spectroscopy chemistry.chemical_element 02 engineering and technology 010402 general chemistry 021001 nanoscience & nanotechnology Dipicolinic acid 01 natural sciences Interfacial polymerization 0104 chemical sciences Polyester chemistry.chemical_compound Molecular geometry chemistry Yield (chemistry) Polymer chemistry Materials Chemistry 0210 nano-technology Tin Alkyl |
| Zdroj: | Journal of Inorganic and Organometallic Polymers and Materials. 26:1338-1350 |
| ISSN: | 1574-1451 1574-1443 |
| DOI: | 10.1007/s10904-016-0424-5 |
| Popis: | The interfacial polymerization is employed to produce high polymer poly(ester ethers) from the reaction of the salt of dipicolinic acid and various organotin dihalides. They are rapidly synthesized with yield increasing as the length of the organotin alkyl chain increases. Infrared spectroscopy shows the formation of new bands derived from the Sn–O and Sn–O(CO) linkages. IR also shows that the products exist as a combination of molecular geometries about the tin atom. MALDI MS shows formation of ion fragment clusters to five and six units in length. The products show good inhibition of a variety of cancer cell lines including two pancreatic cancer cell lines. |
| Databáze: | OpenAIRE |
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