Clinical outcomes after colchicine overdose
| Autor: | He Zhao, Mingjie Fu, Anwei Lu, Jie Zhao, Zhitao Li |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Colchicine overdose
biology Cell division business.industry Lethal dose macromolecular substances General Medicine Pharmacology 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Tubulin chemistry Microtubule 030220 oncology & carcinogenesis biology.protein Distribution (pharmacology) Colchicine Medicine 030212 general & internal medicine business Intracellular |
| Zdroj: | Medicine. 98:e16580 |
| ISSN: | 1536-5964 0025-7974 |
| DOI: | 10.1097/md.0000000000016580 |
| Popis: | Rationale:Colchicine can inhibit cell division and intracellular transport in affected organs by fixing intracellular tubulin and preventing its polymerization into microtubules. A lethal dose of colchicine is considered to be 0.8 mg/kg. The wide distribution of colchicine through 70% of the |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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