Noncatalytic Electrophilic Oxyalkylation of 3-Aminopyrazoles with 2-(Trifluoroacetyl)-1,3-azoles

Autor:	Andrey A. Tolmachev, Pavel K. Mykhailiuk, Pavel V. Khodakovskiy, Dmitriy M. Volochnyuk
Rok vydání:	2010
Předmět:	Chemistry Organic Chemistry Electrophile Medicinal chemistry Catalysis
Zdroj:	Synthesis. 2010:1195-1199
ISSN:	1437-210X 0039-7881
DOI:	10.1055/s-0029-1218657
Popis:	2-(Trifluoroacetyl)-1,3-azoles reacted with 3-aminopyrazoles to give the corresponding trifluoromethyl-substituted alcohols. The conditions required for the reaction and the yields of the products were highly dependent on the electronic nature of the both the 1,3-azole and the 3-aminopyrazole units.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::af0b1fdef0a7a660b647ae98325b3723 https://doi.org/10.1055/s-0029-1218657 Zobrazit plný text záznamu