| Popis: |
Quantitative description of blood platelet shape and its dramatic change during activation is necessary for the correct interpretation of light-scattering data, routinely measured in diagnostic laboratories. We propose the model of platelet shape, based on the known information on the cell cytoskeleton. The model geometry is characterized by two parameters: the cell volume and the overcurvature of the internal microtubule bundle, which changes during platelet activation. We describe the procedure for the construction of a cell shape given the volume and overcurvature, and also the way for simulation of light scattering by such objects. |
