A phase IB study evaluating BSI-201 in combination with chemotherapy in subjects with advanced solid tumors

Autor:	B. M. Sherman, N. Lewis, Monica M. Mita, J. Rodon, Patricia LoRusso, C. R. Bradley, Anthony W. Tolcher, J. J. Mahany, Elisabeth I. Heath, Kyri Papadopoulos
Rok vydání:	2008
Předmět:	Cancer Research Chemotherapy chemistry.chemical_compound Oncology chemistry business.industry medicine.medical_treatment Phase (matter) Cancer research medicine Iniparib business Small molecule
Zdroj:	Journal of Clinical Oncology. 26:3579-3579
ISSN:	1527-7755 0732-183X
DOI:	10.1200/jco.2008.26.15_suppl.3579
Popis:	3579 Background: BSI-201 is a small molecule believed to achieve its anti-neoplastic effect by covalently binding and inhibiting PARP-1, and thus expected to potentiate the damage induced by chemot...
Databáze:	OpenAIRE
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