| Autor: |
S. M. J. Afzal, S. S. Parr, John Lyman, J. Howard, T. S. Tenforde, Stanley B. Curtis |
| Rok vydání: |
1982 |
| Předmět: |
|
| Zdroj: |
Radiation Research. 92:208 |
| ISSN: |
0033-7587 |
| DOI: |
10.2307/3575856 |
| Popis: |
Cell survival curves were measured by the in vivo to in vitro assay procedure for rat rhabdomyosarcoma tumors irradiated in the distal 4-cm extended-peak region of a 670-MeV/u silicon-ion beam. RBE values determined relative to 225-kVp X rays for the killing of oxygenated tumor cells were 2.1 and 2.2 at the 1 and 10% survival levels, respectively. These RBE values are greater than those obtained previously for extended-peak carbon ions (1.7-1.8), but less than those obtained for extended-peak neon ions (2.5-2.7). This observation indicates that the RBE obtained in the distal-peak region of the 670 MeV/u silicon-ion beam lies beyond the maximum in the RBE versus ${\rm LET}_{\infty}$ curve for the killing of oxygenated tumor cells. The RBE value for the killing of hypoxic tumor cells in this beam was 3.6 at both the 1 and 10% survival levels. This RBE value exceeds the previously measured values for both extended-peak carbon ions (2.0) and extended-peak neon ions (3.1-3.3). OER values m... |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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