| Autor: |
Gustavo Stampone, María Mezzadra, Pablo Stutzbach, Matias Lopez Rosetti, Carla Pessio, Iván Constantin, Martin Ruano, María C. Carrero, Sandra Diaz, Gerardo Masson, Gonzalo R. Díaz Babio, Facundo Verón |
| Rok vydání: |
2021 |
| Předmět: |
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| Popis: |
Patients with bicuspid aortic valve (BAV) represent a significant proportion of adults with severe aortic stenosis (AS) requiring aortic valve intervention (AVI). Evidence is discordant concerning progression of AS in BAV. The aim of this study was to compare baseline characteristics and the impact of the aortic valve phenotype on major cardiovascular outcomes. Methods: Retrospective observational study (consecutive AS in database, 2014-2016, third-level institution). Baseline characteristics were compared between BAV (n = 43) and tricuspid (TAV) (n = 159) patients. Primary end point was a composite of mortality and AVI. Survival analysis and logistic regression analysis was used to identify predictors of primary end-point. Results: 202 patients (72.2 ± 13.4 years, 63% men) were included. Patients with TAV were older, had more comorbidities and less aorta dilation. No significant differences were observed in the primary end point between the two valve phenotypes (34.8 vs. 40.8%; p=0.47, follow-up of 3.2 ± 1.6 years). In BAV group most of the events were at the expense of AVI (32.5 vs. 13.8%; p=0.001). The incidence of CV death was similar between both groups (4.8% vs. 12%, p=0.25). Non-CV mortality was higher in TAV group (16.8% vs 0%, p=0.001). Vmax and dimensionless index were independently associated with primary end point (p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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