Replicon Particle Administration Prior to Challenge Reduces PRRSV Viremia

Autor:	Ryan Vander Veen, D.L. Hank Harris, Mark Mogler, Kurt Kamrud
Rok vydání:	2012
Předmět:	business.industry viruses animal diseases virus diseases Viremia biochemical phenomena metabolism and nutrition Placebo medicine.disease Virology Vaccination Immune system Medicine Replicon business
DOI:	10.31274/ans_air-180814-172
Popis:	Vaccination of swine with an alphavirus-derived replicon particle vaccine stimulates a non-specific immune response. This effect was seen when animals were challenged with PRRSV at 24 hours post-vaccination. Animals that received vaccine had reduced viremia as measured by quantitative RT-PCR when compared to placebo. These results highlight the potential of replicon particle vaccines to induce robust immune responses in swine.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ae8abf37b1616f596e1a62c26ac070ef https://doi.org/10.31274/ans_air-180814-172 Zobrazit plný text záznamu