The effect of ethanol extract from Portulaca oleracea on inhibiting total cholesterol on animal subjects
| Autor: | Sulaeman Al Jati, Suci Nar Vikasari, Fahmy Ahsanul Haq, Afifah Bambang Sutjiatmo |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Purslane extract Pharmaceutical Science Pharmacy Portulaca Body weight Education 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Total cholesterol Medicine Ethanol biology Traditional medicine Cholesterol business.industry biology.organism_classification 030104 developmental biology chemistry Simvastatin 030220 oncology & carcinogenesis lipids (amino acids peptides and proteins) Propylthiouracil business medicine.drug |
| Zdroj: | Pharmacy Education. 21:22-26 |
| ISSN: | 1477-2701 1560-2214 |
| Popis: | Introduction: Hypercholesterolemia occurs when cholesterol levels in the blood increases. Traditionally, krokot (purslane, portulaca oleracea) is used to treat cardiovascular disease. Aim: This research evaluated the effect of purslane extract to inhibit increasing of cholesterol levels. Methods: The ethanol extract dosage of purslane was 27.5, 55, and 110 mg/kg body weight (bw) and simvastatin 1.8 mg/kg bw were used as comparisons. The anti-hyper cholesterol effect test was done by feeding a high cholesterol diet and drinks containing 0.01% propylthiouracil. The test parameters were body weight and total cholesterol levels on days 0, 7, 14, and 21. Results: The results showed that the extract was able to prevent the increase in body weight compared to the control group (p0.05). |
| Databáze: | OpenAIRE |
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