The Urgent Need to Understand Covid-19 Associated Coagulopathies and the Significance of Thrombotic Prophylaxis in Critically Ill Patients
| Autor: | Nihaal Singh, Shivangi Garima, Ashish Anjankar |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Coronavirus disease 2019 (COVID-19) Critically ill business.industry Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) 030206 dentistry Disease World health 03 medical and health sciences 0302 clinical medicine Deep vein thromboses Intensive care Pandemic medicine 030212 general & internal medicine Intensive care medicine business |
| Zdroj: | Journal of Evolution of Medical and Dental Sciences. 9:2381-2385 |
| ISSN: | 2278-4802 2278-4748 |
| DOI: | 10.14260/jemds/2020/516 |
| Popis: | BACKGROUND COVID-19 is a novel disease caused due to infection from the respiratory pathogen SARS CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) It originated from the city of Wuhan in China in December 2019, and spread to become a pandemic in most of the world The World Health Organization (WHO) declared COVID-19 to be a `public health emergency of international concern' on January 30, 2020 Since then there have been countless cases and associated fatalities In this article we focus on one aspect of the underlying conditions that may prove to be fatal in critically ill patients of COVID-19, namely hypercoagulative states and their associated thrombotic complications We analyse data-driven studies that outline the manifold increase in instances of COVID-19 related thrombotic events and the patient demography that is most affected by it There are several reflections and critical enumerations of the specific clinical features that patients with COVID-19 associated coagulopathies present with We analyse and comment on several anecdotal instances of patients presenting with new-onset symptoms of severe large-vessel ischemic strokes and other coagulopathies We determine how laboratory findings and specific markers can help identify patients most at risk of thrombotic events These events may range from deep vein thromboses to fatal cerebrovascular accidents There is an increased stress on how these coagulation problems may relate to other infectious conditions through presentation with similar markers We also analyse the radiological investigations that such patients yield and identify peculiarities in them There is further emphasis on the importance and efficacy of thrombotic prophylaxis and anticoagulant therapy in the management and reduction of fatalities We also attempt to educate clinicians and intensive care providers regarding better management practices to mitigate fatal outcomes, including both pharmacological and supportive interventions |
| Databáze: | OpenAIRE |
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