Perbandingan Aktivitas Antifungi Ekstrak Etanol 70% Dan 96% Buah Parijoto (Medinilla speciosa) Terhadap Candida albicans

Autor: Rissa Laila Vifta, Richa Yuswantina, Puji Astutik
Rok vydání: 2021
Zdroj: Journal of Holistics and Health Science. 3:32-41
ISSN: 2686-3812
Popis: Parijoto fruit (Medinilla speciosa) contains active compounds of flavonoids, tannins, saponins, glycosides. Parijoto fruit (Medinilla speciosa) has many benefits for human health, one of which is as an anti-fungal. In this study, the antifungal activity test of 70% ethanol extract and 96% ethanol extract of parijoto fruit (Medinilla speciosa) was tested against Candida albicans. This research was conducted by maceration using 70% ethanol and 96% ethanol as solvents. While the anti-fungal activity used the disc diffusion method using a concentration variation of 2.5% w / v; 5% w / v and 10% w / v using the ratio of ketoconazole antibiotics. Parijoto fruit extract (Medinilla speciosa) obtained 70% (%) ethanol and 96% (%) ethanol. Ethanol 70% with a concentration of 2.5% w / v of 25.83 mm; 5% w / v was 27.03 mm and 10% w / v was 28.03 mm, while the ethanol extract of 96% parijoto fruit (Medinilla speciosa) at a concentration of 2.5% w / v was 31.59 mm; 5% w / v of 33.24 mm and 10% w / v of 36.11 mm. The statistical results of 70% ethanol and 96% ethanol, both of which have anti-fungal activity, are not much different, as evidenced by the T-Test statistical test with a P-Value of 0.00
Databáze: OpenAIRE