Synovial Fluid Hydroxyproline Fractions Before and After Osmic Acid Treatment in Rheumatoid Arthritis
| Autor: | S. Orloff, V. H. Rao, D. Manicourt |
|---|---|
| Rok vydání: | 1981 |
| Předmět: |
medicine.medical_specialty
Pathology business.industry Immunology General Medicine Joint effusion medicine.disease Surgery Hydroxyproline chemistry.chemical_compound Rheumatology chemistry Effusion Osmic Acid Rheumatoid arthritis medicine Immunology and Allergy Synovial fluid In patient medicine.symptom business |
| Zdroj: | Scandinavian Journal of Rheumatology. 10:43-48 |
| ISSN: | 1502-7732 0300-9742 |
| DOI: | 10.1080/03009748109095270 |
| Popis: | Synovial fluid total, dialysable and non-dialysable hydroxyproline were determined in patients with Rheumatoid Arthritis before intra-articular osmic acid injection and on days 2 and 4 after this local treatment. On day 2 the increase in dialysable hydroxyproline paralleled the increase in non-dialysable hydroxyproline. Patients with the highest pre-treatment dialysable hydroxyproline levels also had the highest levels of this fraction on day 2 suggesting that articular damage proceeds after osmic acid injection. However, on day 4 dialysable hydroxyproline levels were consistently lower than before the treatment; the same pattern was observed with non-dialysable hydroxyproline, except for all the joints but one, where effusion recurred 6–12 months after osmic acid treatment. This study suggests that the determination of synovial fluid non-dialysable levels 4 days after osmic acid injection may provide a clue to the prediction of recurrent joint effusion and possibly justify a complementary injection eithe... |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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