Microtubule-dependent pushing forces contribute to long-distance aster movement and centration inXenopus laevisegg extracts

Autor:	Jesse C. Gatlin, Taylor Sulerud, Guihe Li, Abdullah Bashar Sami, John Oakey, April M. Kloxin
Rok vydání:	2020
Předmět:	Cytoplasmic dynein 0303 health sciences biology Xenopus Cell Biology Aster (cell biology) biology.organism_classification Centration 03 medical and health sciences 0302 clinical medicine Microtubule Biophysics Molecular Biology 030217 neurology & neurosurgery 030304 developmental biology
Zdroj:	Molecular Biology of the Cell. 31:2791-2802
ISSN:	1939-4586 1059-1524
Popis:	In this work, we demonstrate that microtubule asters are able to center in a variety of cell geometries and can do so over long distances, even when the activity of cytoplasmic dynein is inhibited. This observation, along with additional characterizations of aster movements, is consistent with a microtubule-based pushing mechanism.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ae246f90d6e56acabe8648ff6613756d https://doi.org/10.1091/mbc.e20-01-0088 Zobrazit plný text záznamu